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Updated: May 25, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
HIV management by nurse prescribers compared with doctors at a paediatric centre in Gaborone, Botswana
Gadzikanani Monyatsi1, Paul C Mullan, Benjamin R Phelps
1Botswana-Baylor Children's Clinical Centre of Excellence, Gaborone, Botswana.
Insights
Trained nurses and doctors showed similar compliance with paediatric HIV treatment guidelines in Botswana. This supports task shifting to nurses for quality care and sustained antiretroviral therapy services for children.
Area of Science:
- Public Health
- Infectious Diseases
- Nursing Practice
Background:
- Paediatric HIV treatment requires adherence to national guidelines.
- Provider shortages in southern Africa necessitate efficient care delivery models.
- Task shifting can potentially improve access to antiretroviral therapy (ART).
Purpose of the Study:
- To compare adherence to paediatric HIV treatment guidelines between nurse prescribers and physicians.
- To evaluate the quality of care provided by nurses versus doctors in Botswana.
- To assess the implications of task shifting in paediatric HIV management.
Main Methods:
- A cross-sectional study was conducted at a paediatric referral centre in Gaborone, Botswana.
- Retrospective chart review of 100 physician and 97 nurse prescriber encounters.
- Evaluation of documentation for eight key clinical variables, including WHO staging and paediatric dosing.
Main Results:
- Nurse prescribers achieved 96.0% compliance, while physicians achieved 94.9% compliance.
- No significant differences were observed in most documentation items between nurses and physicians.
- A trend suggested higher social history documentation rates among nurse prescribers.
Conclusions:
- Findings support investing in trained nurses for quality ART services for stable HIV-infected children.
- Task shifting is a viable strategy to scale up ART services amidst provider shortages.
- ART service policies should not limit essential services to physicians, especially in resource-limited settings.
Objectives:
To compare compliance with national paediatric HIV treatment guidelines between nurse prescribers and doctors at a paediatric referral centre in Gaborone, Botswana.
Methods:
A cross-sectional study was conducted in 2009 at the Botswana-Baylor Children's Clinical Centre of Excellence (COE), Gaborone, Botswana, comparing the performance of nurse prescribers and physicians caring for HIV-infected paediatric patients. Selected by stratified random sampling, 100 physician and 97 nurse prescriber encounters were retrospectively reviewed for successful documentation of eight separate clinically relevant variables: pill count charted; chief complaint listed; social history updated; disclosure reviewed; physical exam; laboratory testing; World Health Organization (WHO) staging documented; paediatric dosing.
Results:
Nurse prescribers and physicians correctly documented 96.0% and 94.9% of the time, respectively. There was a trend towards a higher proportion of social history documentation by the nurses, but no significant difference in any other documentation items.
Conclusions:
Our findings support the continued investment in programmes employing properly trained nurses in southern Africa to provide quality care and ART services to HIV-infected children who are stable on therapy. Task shifting remains a promising strategy to scale up and sustain adult and paediatric ART more effectively, particularly where provider shortages threaten ART rollout. Policies guiding ART services in southern Africa should avoid restricting the delivery of crucial services to doctors, especially where their numbers are limited.
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