Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

X-linked congenital retinoschisis.

U Kellner1, S Brümmer, M H Foerster

  • 1Zentrum für Augenheilkunde, Universität Essen, Federal Republic of Germany.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|January 1, 1990
PubMed
Summary

X-linked congenital retinoschisis typically causes reduced visual acuity that remains stable. Complications like retinal detachment can occur but are often treatable.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heart Transplantation in Systemic Sclerosis: New Impulses for Conventional Scleroderma Transplantation Regimen and Scleroderma Diagnostic Monitoring: 2 Case Reports.

Transplantation proceedings·2019
Same author

[History of pathology-from the first autopsies to the near future : A new series of articles in Der Pathologe].

Der Pathologe·2019
Same author

[History of the anatomical and clinical autopsy].

Der Pathologe·2018
Same author

[Hereditary Macular Dystrophies].

Klinische Monatsblatter fur Augenheilkunde·2016
Same author

[Spectral Reflectance Retinal Imaging: Clinical Evaluation].

Klinische Monatsblatter fur Augenheilkunde·2015
Same author

[Surprise in abrasion diagnostics].

Der Pathologe·2015

Area of Science:

  • Ophthalmology
  • Genetics
  • Clinical Medicine

Background:

  • X-linked congenital retinoschisis (XLRS) is a hereditary retinal disorder.
  • Understanding its natural history and electrophysiological characteristics is crucial for patient management.

Purpose of the Study:

  • To describe the long-term natural history of XLRS.
  • To detail electrophysiological findings in patients with XLRS.
  • To evaluate treatment outcomes for XLRS complications.

Main Methods:

  • Longitudinal study of 52 patients with XLRS.
  • Follow-up period of up to 26 years.
  • Assessment of visual acuity, complications (retinal detachment, vitreous hemorrhage), and electrophysiological tests (electroretinogram, electrooculogram).

Related Experiment Videos

Main Results:

  • Mean visual acuity was 0.24 +/- 0.2, largely stable over time.
  • Visual loss primarily occurred within the first decade.
  • Retinal detachments (11%) and vitreous hemorrhages (4%) were observed; detachments had a 40% reoccurrence rate after treatment.
  • Electrocorticography showed normal a-waves, reduced b-waves, prolonged b-wave latencies, and reduced 30 Hz flicker response.

Conclusions:

  • XLRS is characterized by stable, reduced visual acuity in most patients.
  • Retinal detachments are a significant complication requiring surgical intervention.
  • Electrophysiological findings include specific alterations in electroretinogram parameters.