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Is radical hysterectomy always necessary in early cervical cancer?
A Jakobsen1, P Bichel, S Ahrons
1Department of Oncology, Aarhus University Hospital, Denmark.
Gynecologic Oncology
|October 1, 1990
Abstract:
A semiquantitative histopathologic grading system was used in combination with flow cytometric measurements of tumor cell DNA content to predict the risk of lymph node metastases in early cervical cancer. A retrospective study of 126 stage IB patients showed that a group with no risk of lymph node involvement could be identified by the use of both the histopathologic score and the DNA index. The results were confirmed in a prospective investigation of 59 new patients. Simple hysterectomy may be advised in low-risk patients.