Related Experiment Video
Updated: May 25, 2026

07:35
A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer
Published on: December 26, 2016
Muscle metastases from gallbladder cancer
1Division of Nuclear Medicine, European Institute of Oncology, via Ripamonti 435, 20141 Milano, Italy.
Ecancermedicalscience
|January 26, 2012
Summary
Gallbladder cancer can spread to unusual sites like muscles. FDG-PET/CT detected unexpected muscle and lung metastases in a patient previously treated for gallbladder cancer.
Area of Science:
- Oncology
- Medical Imaging
Background:
- Gallbladder cancer is aggressive with a poor prognosis, often diagnosed at advanced stages.
- Common metastasis sites include lymph nodes, liver, and peritoneum.
- Rare metastatic sites like thyroid and breast have been documented.
Observation:
- A patient with a history of gallbladder cancer presented with persistent haemoptysis.
- FDG-PET/CT imaging was performed due to the persistent symptoms.
- The imaging revealed unsuspected metastases.
Findings:
- The patient exhibited unexpected muscle metastases.
- Pulmonary metastases were also detected concurrently.
- These findings were identified in a patient with a history of gallbladder cancer.
Implications:
- This case highlights the potential for gallbladder cancer to metastasize to muscle tissue.
- FDG-PET/CT is a valuable tool for detecting unusual metastatic spread.
- Understanding rare metastatic patterns is crucial for accurate diagnosis and patient management.
Related Concept Videos
Gallbladder
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Cholecystitis
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

