Related Experiment Video
Updated: May 25, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
Chilblains and microgeodic disease diagnosed concurrently in a child's toe
Brea Prindaville1, Richard J Antaya
1Department of Pediatrics, Yale New Haven Hospital, New Haven, Connecticut 06510, USA. brea.prindaville@yale.edu
Abstract:
Microgeodic disease, similar to chilblains (pernio), is characterized by painful, erythematous swelling, as well as small, punched-out erosions found in affected phalanges. Although they share a similar appearance and proposed pathogenesis, chilblains has rarely been diagnosed in children with microgeodic disease, and in those cases has not been confirmed on skin biopsy. This article details a child in Connecticut diagnosed during the winter with chilblains and microgeodic disease of his toe, as supported by biopsy and imaging. These findings further indicate that the two diseases are interrelated, imply a similar pathogenesis, and lead us to suggest similar treatment for problematic forms of both diseases.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Diabetic Foot Ulcer
Fungal Phylum Microsporidia
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...