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Cocaine and fetal death.

I Morild1, M Stajic

  • 1Department of Forensic Medicine, Gade Institute, University of Bergen, Norway.

Forensic Science International
|September 1, 1990
PubMed
Summary

Maternal cocaine use is linked to fetal death, with cocaine or its metabolites found in 64% of cases. Toxicologic screening is crucial for understanding these tragic outcomes.

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Area of Science:

  • Forensic Toxicology
  • Perinatal Medicine
  • Obstetrics

Background:

  • Maternal drug use, particularly cocaine, poses significant risks to fetal development and survival.
  • Fetal death necessitates thorough investigation to determine underlying causes, including toxicological factors.

Purpose of the Study:

  • To investigate the prevalence of cocaine and its metabolites in cases of fetal death.
  • To explore the association between maternal cocaine use and adverse pregnancy outcomes such as fetal demise.

Main Methods:

  • Toxicologic screening for cocaine and its metabolites was conducted on blood and brain tissue samples.
  • Autopsy reports from 103 fetal death cases were analyzed.
  • Data were collected from the Office of the Chief Medical Examiner, City of New York.

Main Results:

  • Cocaine or its metabolites were detected in 64 out of 103 cases (approximately 62%).
  • Some cases exhibited fetal malformations in addition to the presence of cocaine.
  • The findings suggest a correlation between maternal cocaine use and fetal death.

Conclusions:

  • Maternal cocaine use is a significant risk factor for abruptio placentae, abortion, and fetal death.
  • Routine toxicologic examination is essential in the autopsy of fetal death cases to identify drug exposure.
  • Understanding the toxicological profile of fetal demise cases aids in public health interventions and prevention strategies.

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