Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Components of Stress01:23

Components of Stress

Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and opposite to those on the...
Stress01:20

Stress

When a force is applied on a body, it undergoes deformation. In order to restore the body to its original shape and/or size, an opposite or restoring force is generated within the body. This restoring force is equal to the magnitude of the applied force, but acts in the opposite direction. The amount of this restoring force developed per unit area of the body is called stress. Stress is a tensor quantity and has the SI unit pascal. Stress can be separated into four broad categories depending...
Psychological Responses to Stress01:20

Psychological Responses to Stress

Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre-existing and de novo postoperative depression.

Epileptic disorders : international epilepsy journal with videotape·2026
Same author

Moderators and predictors of treatment outcome for OCD: A comparison of cognitive behavioral therapy Exposure Response Prevention to Acceptance and Commitment Therapy.

Psychotherapy research : journal of the Society for Psychotherapy Research·2026
Same author

Time trends of incidence and prevalence of severe mental illness in Danish adults: a nationwide register study.

Nordic journal of psychiatry·2026
Same author

Prevalence and types of anxiety disorders among patients with cardiac conditions and elevated HADS-A scores: findings from the initial screening phase of the Heart and Mind trial in Denmark.

BMJ open·2026
Same author

Prevention of Recurrent Cases of Emergence Delirium in Electroconvulsive Therapy.

Cureus·2026
Same author

A novel model for percentile-based oscillometric blood pressure reference values in Danish children: implications for the use of international standards in pediatric screening.

European journal of pediatrics·2026

Related Experiment Video

Updated: May 25, 2026

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
07:26

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Published on: May 4, 2020

[Stress and aging].

Anders Jørgensen1, Martin Balslev Jørgensen, Henrik Enghusen Poulsen

  • 1Psykiatrisk Center København, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark. anders.01.joergensen@regionh.dk

Ugeskrift for Laeger
|January 27, 2012
PubMed
Summary

Psychological stress accelerates aging by impacting cellular systems and increasing the risk of age-related diseases, primarily through stress hormone secretion. This review examines biochemical and epidemiological data linking stress and the aging process.

Area of Science:

  • Biomedical Science
  • Gerontology
  • Psychoneuroimmunology

Context:

  • Psychological stress is increasingly recognized as a significant factor influencing physiological processes.
  • Cellular aging mechanisms are complex and influenced by various environmental and internal factors.
  • Age-related diseases pose a growing public health challenge.

Purpose:

  • To review the biochemical and epidemiological evidence connecting psychological stress and accelerated aging.
  • To elucidate the role of stress hormones in mediating the relationship between stress and aging.
  • To synthesize current understanding of stress-induced aging.

Summary:

  • Psychological stress states are linked to accelerated aging processes.
  • Stress impacts cellular aging pathways and elevates the risk of age-related medical conditions.

More Related Videos

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
06:15

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

Related Experiment Videos

Last Updated: May 25, 2026

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
07:26

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Published on: May 4, 2020

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents
06:15

A Modified Trier Social Stress Test for Vulnerable Mexican American Adolescents

Published on: July 10, 2017

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
07:13

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice

Published on: October 24, 2018

  • Stress hormones are identified as key mediators in the stress-aging nexus.
  • Impact:

    • Provides a concise overview of the scientific basis for the link between stress and aging.
    • Highlights the role of stress hormones in the aging process.
    • Informs future research directions in gerontology and stress-related disorders.