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[Acquired immunodeficiency].

H W Kreth1

  • 1Kinderklinik Universität Würzburg.

Fortschritte Der Medizin
|September 20, 1990
PubMed
Summary

Secondary immunodeficiencies are common, often caused by factors like malnutrition or infections. Viruses like measles and HIV (human immunodeficiency virus) are significant causes of acquired immune deficiency.

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Area of Science:

  • Immunology
  • Virology
  • Infectious Diseases

Context:

  • Secondary immunodeficiencies are more prevalent than primary ones.
  • Multiple factors contribute to secondary immunodeficiencies, including malnutrition, medical treatments, and infections.
  • Viral infections represent a notable category of secondary immunodeficiency causes.

Purpose:

  • To review the historical context and current significance of virus-induced immunosuppression.
  • To highlight key viral etiologies of acquired immune deficiency diseases.
  • To emphasize the importance of considering viral causes in immunological disorders.

Summary:

  • Secondary immunodeficiencies, more common than primary disorders, arise from diverse causes like malnutrition, drug therapy, burns, and infections.
  • This review focuses on virus-induced immunosuppression, identifying measles and acquired immunodeficiency syndrome (AIDS) as primary examples.
  • Epstein-Barr virus is also noted for its potential to cause hypogammaglobulinemia and B cell lymphomas.

Impact:

  • Underscores the significant role of viral infections in acquired immune deficiency.
  • Highlights the need for considering viral etiologies in both congenital and acquired immunological conditions.
  • Provides a concise overview of important virus-induced immunodeficiency diseases for clinicians and researchers.

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