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Related Concept Videos

Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

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Related Experiment Video

Updated: May 25, 2026

Application of Monolayer Graphene to Cryo-Electron Microscopy Grids for High-resolution Structure Determination
07:57

Application of Monolayer Graphene to Cryo-Electron Microscopy Grids for High-resolution Structure Determination

Published on: November 10, 2023

Complementary microscopy techniques applied for optimizing the structure and performance of graphene-based hybrids.

Wen Qian1, Zhiqiang Chen, Micah Eastman

  • 1Department of Physics, Portland State University, Portland, OR 97201, USA.

Ultramicroscopy
|January 27, 2012
PubMed
Summary

Hybridizing graphene with metal/metal oxide nanocrystals enhances performance for green energy. Energy-filtered transmission electron microscopy (EFTEM) is crucial for optimizing these graphene-based composites.

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Fabrication of Gate-tunable Graphene Devices for Scanning Tunneling Microscopy Studies with Coulomb Impurities
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Published on: July 24, 2015

Area of Science:

  • Materials Science
  • Nanotechnology
  • Green Energy

Background:

  • Hybridizing graphene with metal/metal oxide nanocrystals (NCs) is key to enhancing its performance and expanding applications.
  • Graphene-based hybrids are promising for green energy technologies.

Purpose of the Study:

  • To demonstrate complementary characterization techniques for optimizing graphene-based hybrids.
  • To explore the utility of energy-filtered transmission electron microscopy (EFTEM) for analyzing graphene/metal oxide nanocomposites.

Main Methods:

  • X-ray diffraction (XRD)
  • High-resolution electron microscopy (HREM)
  • Energy-dispersive X-ray spectroscopy (EDX)
  • Energy-filtered transmission electron microscopy (EFTEM)

Main Results:

  • EFTEM elemental mapping identified that cobalt NC oxidation in graphene/CoO(x) occurred during post-treatment.
  • 2D elemental mapping with EFTEM differentiated the distribution of Mn, Co, and Ni on graphene surfaces in graphene/(Mn, Co, Ni)O(x).

Conclusions:

  • EFTEM provides critical information for evaluating the structure and performance of graphene-based hybrids.
  • Optimized synthesis and characterization of graphene NC hybrids are essential for advancing green energy applications.