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Updated: May 25, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Study of relationship between clinical factors and velopharyngeal closure in cleft palate patients
Qi Chen1, Qian Zheng, Bing Shi
1Postgraduate, State Key Laboratory of Oral Disease, West China College of Stomatology, Sichuan University, Chengdu, PR China.
Background:
This study was carried out to analyze the relationship between clinical factors and velopharyngeal closure (VPC) in cleft palate patients.
Methods:
Chi-square test was used to compare the postoperative velopharyngeal closure rate. Logistic regression model was used to analyze independent variables associated with velopharyngeal closure.
Results:
Difference of postoperative VPC rate in different cleft types, operative ages and surgical techniques was significant (P=0.000). Results of logistic regression analysis suggested that when operative age was beyond deciduous dentition stage, or cleft palate type was complete, or just had undergone a simple palatoplasty without levator veli palatini retropositioning, patients would suffer a higher velopharyngeal insufficiency rate after primary palatal repair.
Conclusions:
Cleft type, operative age and surgical technique were the contributing factors influencing VPC rate after primary palatal repair of cleft palate patients.
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