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Updated: May 25, 2026

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
Published on: December 1, 2017
[Gender differences of acute pyelonephritis in the North]
Abstract:
To investigate results of treatment in patients with acute pyelonephritis (AP) among the population of giving age in the North of Russia for prognostication of the disease and decision on further therapy, we studied 1109 case histories of patients treated for urinary infections (UI) including 794 patients with pyelonephritis (119 with AP). Age of both males and females with AP was younger than of UI patients. AP among female inpatients with UI occurred twice more frequently than in males. Ascending AP was characterized by dysuria, mild lumbar pain, symptoms of general intoxication, leukocyturia, bacteriuria, moderate leukocytosis, elevated leukocytic intoxication index (LII) both in males and females. Hematogenic AP in young males presented with lumbar pain, symptoms of general intoxication, leukocytosis, LII elevation in the absent or mild leukocyturia. The main route of renal infection in population of giving age in the North in AP - ascending. Hematogenic route of infection occurs in young males and is typical for pyodestructive AP.
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