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Auditory brainstem evoked responses in healthy north Indians
1Department of Physiology, University College of Medical Sciences, Delhi.
The Indian Journal of Medical Research
|August 1, 1990
Summary
This study establishes normative auditory brainstem evoked potential (ABR) response data for healthy Indian adults and children. Findings reveal age-independent interpeak latencies but significant sex-based differences in ABR values.
Area of Science:
- Neuroscience
- Audiology
- Clinical Electrophysiology
Background:
- Auditory brainstem evoked potential (ABR) testing is crucial for assessing auditory pathway function.
- Establishing normative data is essential for accurate clinical interpretation of ABR results.
- Previous studies have reported ABR normative data, but regional variations and sex-specific differences require further investigation.
Purpose of the Study:
- To establish normative data for auditory brainstem evoked potential (ABR) responses in a healthy Indian population.
- To analyze age-related and sex-related differences in ABR parameters, including absolute and interpeak latencies and wave amplitudes.
- To provide reference values for clinical application in audiological assessments.
Main Methods:
- Auditory brainstem evoked potential (ABR) responses were recorded from 132 healthy subjects across four age groups ( <15, 16-25, 26-45, >46 years).
- Data collection involved CZ-A1 and A2 scalp regions.
- Analysis focused on absolute and interpeak latencies (IPLs) of waves I, III, and V, and amplitudes of waves I and V, with sex-specific data and 99% tolerance limits calculated.
Main Results:
- Mean interpeak latencies (IPLs) I-III, III-V, and I-V were found to be 2.09, 1.85, and 3.97 msec, respectively, showing no significant age dependency.
- Significant sex-related differences were observed in IPLs, with distinct normative values provided for males and females.
- Male IPLs: I-III 2.13 (2.58 TL), III-V 1.88 (2.30 TL), I-V 4.03 (4.48 TL) msec; Female IPLs: I-III 2.05 (2.44 TL), III-V 1.80 (2.25 TL), I-V 3.89 (4.42 TL) msec.
Conclusions:
- The established normative ABR data for Indian subjects are comparable to international standards.
- Age is not a significant factor for interpeak latencies in healthy individuals within the studied ranges.
- Sex-specific normative values for ABR interpeak latencies are necessary for accurate interpretation in clinical audiology.