Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barriers and facilitators to the implementation of virtual reality as a pain management intervention in outpatient physiotherapy practices: a qualitative analysis.

BMC health services research·2026
Same author

Self-touch versus muscle relaxation: Short-term benefits for physical well-being and body appreciation.

Acta psychologica·2026
Same author

Another Differentiated Look at Emotions: A Replication Study on Associations Between Gaze Behavior During the Processing of Affective Videos and Emotional Granularity.

Scandinavian journal of psychology·2026
Same author

Item difficulty of eight tests for the examination of lumbar movement control in flexion in chronic non-specific lumbar back pain - a cross-sectional study.

BMC musculoskeletal disorders·2026
Same author

Acceptance of Open-Label Placebos Is Linked to Holistic Health Beliefs and Thinking Styles.

Behavioral sciences (Basel, Switzerland)·2026
Same author

Eye candy & eye tunes: Effects of liked vs. disliked music on desire to eat and food choice in an eye-tracking buffet paradigm.

Appetite·2025
Same journal

Investigating the Neural Origins of Ear-EEG: A Correlation Study Using Scalp EEG Source Reconstruction.

NeuroImage·2026
Same journal

Hysteresis effects in visual and auditory perception and the comparison of underlying neural mechanisms - an EEG study.

NeuroImage·2026
Same journal

Short-term audio-tactile training affects cortical auditory speech-envelope tracking for incongruent but not congruent stimuli.

NeuroImage·2026
Same journal

Dissociable Neurocognitive Mechanisms of State and Trait Anxiety in Working Memory: Threat-Induced Alterations in Decision Dynamics and Attenuation of Large-Scale Network Reconfiguration.

NeuroImage·2026
Same journal

Neuro-Ocular Amyloid Characterization in Alzheimer's Disease via Cross-Site PET-MRI and Hierarchical Cross-Attention Driven Multimodal Representation Learning.

NeuroImage·2026
Same journal

Whole-brain network dynamics underlying intolerance of uncertainty.

NeuroImage·2026
See all related articles

Related Experiment Video

Updated: May 25, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

fMRI pattern recognition in obsessive-compulsive disorder.

Martin Weygandt1, Carlo R Blecker, Axel Schäfer

  • 1Bernstein Center for Computational Neuroscience Berlin, Charité-Universitätsmedizin Berlin, Germany.

Neuroimage
|January 28, 2012
PubMed
Summary
This summary is machine-generated.

Brain patterns can distinguish obsessive-compulsive disorder (OCD) patients from healthy individuals using functional MRI (fMRI). This research identifies specific brain regions and neural markers for reliable OCD diagnosis.

More Related Videos

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)
06:26

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)

Published on: November 27, 2019

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Related Experiment Videos

Last Updated: May 25, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)
06:26

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)

Published on: November 27, 2019

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Science

Background:

  • Obsessive-compulsive disorder (OCD) involves altered processing of emotional stimuli.
  • Understanding neural differences in OCD is crucial for diagnosis and treatment.

Purpose of the Study:

  • To investigate if brain activity patterns can differentiate between OCD patients and healthy controls when viewing emotional and neutral images.
  • To identify specific brain regions that contain diagnostic information for OCD.

Main Methods:

  • Utilized functional magnetic resonance imaging (fMRI) with multivariate pattern classification techniques.
  • Analyzed brain activity patterns from single fMRI time samples in response to fear, disgust, and neutral stimuli.
  • Employed a searchlight approach to predict diagnostic status based on local brain patterns.

Main Results:

  • Accurately decoded fear-eliciting from neutral stimuli in both OCD patients and healthy controls.
  • Successfully differentiated disgust-inducing from neutral stimuli in healthy controls.
  • Identified the orbitofrontal cortex and caudate nucleus as key regions with 100% accuracy in predicting OCD status.

Conclusions:

  • Multivariate pattern classification of fMRI data can identify reliable neurobiological markers for OCD.
  • The proposed fMRI paradigms show potential for integration into future diagnostic procedures and treatment strategies for OCD.