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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Venous thromboembolism and pregnancy
Maristella D'Uva1, Pierpaolo Di Micco, Ida Strina
1Department of Obstetrics and Gynecology and Human Reproduction, "Federico II" University of Naples, Naples, Italy;
Journal of Blood Medicine
|January 28, 2012
Summary
This study examines hypercoagulable states and adverse pregnancy outcomes like recurrent pregnancy loss (RPL). It highlights the role of antithrombotic treatment in preventing venous thromboembolism (VTE) during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Reproductive Medicine
Background:
- Hypercoagulable states are linked to adverse pregnancy outcomes, particularly recurrent pregnancy loss (RPL).
- Early research focused on thrombophilia and RPL, but later studies explored antithrombotic treatment's role in preventing pregnancy complications.
- Venous thromboembolism (VTE) is a significant vascular complication during pregnancy.
Purpose of the Study:
- To review the association between hypercoagulable states and adverse pregnancy outcomes.
- To evaluate the role of antithrombotic therapy in managing thrombophilia during pregnancy.
- To provide guidance on thromboprophylaxis and antithrombotic treatment for pregnant individuals with VTE or thrombophilia.
Main Methods:
- Literature review of studies on thrombophilia, RPL, and VTE in pregnancy.
- Analysis of the impact of antithrombotic treatments on pregnancy outcomes.
- Synthesis of current evidence regarding thromboprophylaxis strategies.
Main Results:
- A strong association exists between hypercoagulable states and adverse pregnancy outcomes, including RPL.
- Antithrombotic treatment may prevent vascular complications like VTE during pregnancy.
- Thromboprophylaxis is recommended for pregnant individuals with molecular thrombophilia or a history of VTE.
Conclusions:
- Hypercoagulable states significantly impact pregnancy outcomes.
- Antithrombotic therapy is crucial for managing VTE and preventing complications in pregnant patients.
- Proactive thromboprophylaxis and treatment are essential for improving maternal and fetal health in high-risk pregnancies.
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