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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...

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Related Experiment Video

Updated: May 25, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Sexual dysfunction in men with type 2 diabetes.

Maria Luisa Isidro1

  • 1Endocrine Department, Complejo Hospitalario Universitario A Coruña, As Xubias 84, 15006 A Coruña, Spain. ma.luisa.isidro.san.juan@sergas.es

Postgraduate Medical Journal
|January 28, 2012
PubMed
Summary

Sexual dysfunction is common in type 2 diabetic men, with erectile dysfunction being the most studied. Other forms of sexual dysfunction and their treatments in this population require further investigation.

Area of Science:

  • Endocrinology
  • Urology
  • Men's Health

Background:

  • Sexual dysfunction (SD) is prevalent in men with type 2 diabetes mellitus.
  • The global increase in diabetes mellitus is projected to raise the incidence of SD.
  • Existing research primarily focuses on erectile dysfunction, neglecting other forms of SD.

Purpose of the Study:

  • To highlight the commonality of sexual dysfunction in type 2 diabetic men.
  • To underscore the limited diagnosis and treatment of SD in this demographic.
  • To identify research gaps concerning non-erectile forms of SD in diabetic men.

Main Methods:

  • Comprehensive medical and sexual history taking.
  • Physical examination and psychosocial assessment.
  • Consideration of complementary diagnostic studies when necessary.

Related Experiment Videos

Last Updated: May 25, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Main Results:

  • Erectile dysfunction is recognized as an early indicator of systemic disease in diabetic men.
  • Phosphodiesterase type 5 inhibitors are a primary treatment for organic erectile dysfunction.
  • Treatments for premature ejaculation involve SSRIs, clomipramine, or topical anesthetics.
  • Delayed ejaculation and anejaculation due to nerve or vascular damage are often irreversible.

Conclusions:

  • Sexual dysfunction significantly impacts psychological well-being and reproductive function in diabetic men.
  • Addressing modifiable factors is crucial for initial SD treatment.
  • Further research is needed on the treatment of hypoactive sexual desire disorder in diabetic men, excluding hypogonadism-related cases.