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Updated: May 25, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
[Pressure-sensitive neuropathy after obstetric delivery with epidural analgesia]
M Llácer Pérez1, A Vivó Blasco, G Espinosa Martínez
1Servicio de Anestesiología y Reanimación, Empresa Pública Hospital Costa del Sol, Marbella, Málaga. mllacerperez@gmail.com
Abstract:
We report the case of a woman who requested epidural analgesia for labor in whom catheterization of the epidural space was difficult, requiring multiple punctures; furthermore, the epidural block was followed by a long expulsion phase in the delivery room. Shortly after delivery the patient experienced paresthesia and weakness in her lower limbs. A diagnosis of pressure-sensitive, or tomaculous neuropathy was based on clinical observation and neurophysiologic and genetic studies. This hereditary disease, which affects peripheral nerve myelin, involves recurrent episodes of focal demyelination when nerves are injured slightly or compressed. This condition is probably underdiagnosed, as there are very few references to it in the literature on anesthesia.
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