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Updated: May 25, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Neurologic emergencies in patients who have cancer: diagnosis and management
Kelly Jo Baldwin1, Saša A Zivković, Frank S Lieberman
1Department of Neurology, University of Pittsburgh Medical Center, 337C Scaife Hall, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Abstract:
The nervous system can be significantly affected by cancer. Neurologic symptoms are present in 30% to 50% of oncologic patients presenting to the emergency department or in neurologic consultation at teaching hospitals. Evaluation and treatment require collaborative effort between specialties. The causes of neurologic emergencies in patients with cancer are mostly related to effects of cancer, toxicities of treatments, infections, and paraneoplastic syndromes. These complications cause significant morbidity and mortality and require prompt and accurate diagnostic and treatment measures. This article reviews the common neurologic emergencies affecting patients with cancer and discusses epidemiology, clinical presentation, diagnosis, and treatment modalities.
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