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[Rheumatoid arthritis and cardiovascular disease: what is known about this relationship and what can currently be

Alexandre de Matos Soeiro1, Michel Haddad, Maria Carolina Feres de Almeida

  • 1Instituto do Coraçã do do Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil. alexandre.soeiro@bol.com.br

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|January 31, 2012
PubMed

Insights

Rheumatoid arthritis is an independent risk factor for coronary artery disease. This review highlights inflammatory and atherosclerotic mechanisms, suggesting strategies for cardiovascular risk stratification and treatment in rheumatoid arthritis patients.

Area of Science:

  • Cardiovascular Medicine
  • Rheumatology
  • Immunology

Context:

  • Growing interest in autoimmune diseases and their cardiovascular implications.
  • Rheumatoid arthritis (RA) recognized as an independent risk factor for coronary artery disease (CAD).
  • Need for improved risk stratification and treatment strategies for cardiovascular disease (CVD) in RA patients.

Purpose:

  • To review the literature on atherosclerotic and inflammatory mechanisms in CAD.
  • To highlight the importance of these mechanisms in the context of RA.
  • To propose strategies for CVD risk stratification and management in RA.

Summary:

  • RA significantly increases cardiovascular risk, particularly for CAD.
  • Inflammatory and atherosclerotic pathways are key contributors to CVD in RA.
  • Effective risk stratification and targeted therapies are crucial for managing CVD in RA patients.

Impact:

  • Provides a comprehensive overview of CVD risk in RA.
  • Informs clinical practice regarding risk assessment and management.
  • Guides future research into novel therapeutic approaches for reducing cardiovascular risk in RA.

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