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Published on: February 15, 2022
[Post-operative rehabilitation of functional amblyopia in primary infantile glaucoma: 11 year-follow-up]
M Boulze-Pankert1, E Zanin, F Matonti
1Service d'ophtalmologie, hôpital Nord, CHU, chemin des Bourrely, 13015 Marseille, France.
Insights
Prolonged functional amblyopia treatment is crucial for visual recovery in children with primary infantile glaucoma. Good adherence to occlusion therapy significantly improves visual acuity outcomes.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Vision Science
Background:
- Primary infantile glaucoma often leads to functional amblyopia.
- Visual rehabilitation in these children presents unique challenges.
- Early surgical intervention is standard, but visual outcomes require further management.
Purpose of the Study:
- To assess the effectiveness of functional amblyopia treatment in children post-primary infantile glaucoma surgery.
- To identify factors influencing visual acuity recovery in this cohort.
Main Methods:
- Retrospective analysis of 29 eyes from children treated for primary infantile glaucoma.
- Evaluation of parameters including age at surgery, visual acuity, refraction, corneal condition (Haab striae), and adherence to amblyopia treatment.
- Statistical analysis using Pearson's correlation and p-values.
Main Results:
- A mean visual acuity gain of 2.3 over 10 was observed.
- Higher astigmatism negatively correlated with final visual acuity.
- Improved adherence to occlusion therapy positively correlated with visual acuity recovery (gain of 3.2 over 10).
- The presence and organization of Haab striae impacted final visual acuity.
Conclusions:
- Sustained functional amblyopia treatment is essential for optimal visual rehabilitation in primary infantile glaucoma.
- Treatment adherence and corneal status are significant factors in visual outcomes.
Purpose:
To evaluate the efficacy of functional amblyopia treatment in children having undergone surgery for primary infantile glaucoma.
Patients And Method:
Parameters studied included: age at surgery, current age, visual acuity (VA) (initial and most recent acuity), refraction, alignment, adherence to amblyopia treatment, condition of the cornea (Haab striae, stromal scarring, pachymetry, cell count), condition of the optic disc (cupping, RNFL OCT) and intraocular pressure. Pearson's p-value was fixed at 5%.
Results:
Retrospective study of 29 eyes; average age at surgery was four months, mean follow-up was 11.2 years. Initial VA averaged 4.5 over 10, most recent VA 7 over 10, i.e. a gain of 2.3 over 10. Refraction revealed 37.9% myopia, 10.3% emmetropia, 48.2% hyperopia and an average astigmatism of 2.14 D. A negative correlation was found between astigmatism and most recent VA (rho=-0.7; P<0.001). A positive correlation was found between the quality of the occlusion therapy and the recovery of VA with a gain of 3.2 over 10 (P=0.001). A strong positive correlation was found between the cylinder power and the number of Haab striae [rho 0.702, P<0.0001]; final VA is best when the striae show no organized scar formation (P=0.04).
Conclusion:
This study underlines the necessity of prolonged treatment of functional amblyopia in primary infantile glaucoma for the best possible visual rehabilitation.
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