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Published on: November 28, 2025
[Bone (marrow) edema in magnetic resonance imaging - finding or only signal? A brief look behind the mirror]
1Beratungsstelle und Referenzzentrum für Osteoradiologie, Klinikum Bremen-Mitte gGmbH, Friedrich-Karl-Str. 55, 28177, Bremen, Deutschland. freyschmidt@radiologie-freyschmidt.de
Abstract:
An ill-defined area of increased signal intensity in bone marrow seen on water-sensitive magnetic resonance (MR) sequences (e. g. T2, short TI inversion recovery STIR) is usually referred to as "bone marrow edema". It may be observed with traumatic (e.g. bone bruise), inflammatory, osteoarthritic as well as neoplastic processes. Therefore, it can be confusing if the term "bone marrow edema" is used to describe a clinicoradiologic condition or diagnosis. Addressing these imaging findings as "edema equivalent" or "edema-like increased signal intensity" helps to restrict this phenomenon to a magnetic resonance sign and to avoid using it as a radiologic diagnosis. To illustrate this three case examples with corresponding MR images are presented to point out the intention of this article.
Insights
Bone marrow edema on MRI scans can be confusing as it appears in various conditions. Using "edema equivalent" or "edema-like signal intensity" clarifies it as an imaging sign, not a diagnosis.
Area of Science:
- Radiology
- Magnetic Resonance Imaging (MRI)
Background:
- The term "bone marrow edema" is commonly used to describe increased signal intensity in bone marrow on water-sensitive MRI sequences.
- This finding is associated with diverse conditions including trauma, inflammation, osteoarthritis, and neoplasms.
Observation:
- The term "bone marrow edema" can be ambiguous when used as a clinicoradiologic diagnosis.
- Increased signal intensity on MRI is a descriptive imaging sign, not a definitive diagnosis.
Findings:
- Describing these findings as "edema equivalent" or "edema-like increased signal intensity" is recommended.
- This terminology helps differentiate the imaging sign from a specific diagnosis.
Implications:
- Clarifying the terminology improves diagnostic accuracy and communication in radiology.
- Using precise language avoids misinterpretation of MRI findings in clinical practice.
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