Related Experiment Video
Updated: May 25, 2026

10:35
Microvascular Decompression: Salient Surgical Principles and Technical Nuances
Published on: July 5, 2011
[Decompressive craniectomy in acute stroke - The different perspective].
Oliver P Gautschi1, Dieter Cadosch, Martin N Stienen
1Klinik für Neurochirurgie am Universitätsspital Genf. oliver.gautschi@hcuge.ch
Summary
Space occupying strokes cause significant mortality and morbidity due to brain swelling. Decompressive craniectomy (DC) is a surgical option to reduce intracranial pressure when conservative methods fail.
Area of Science:
- Neurology
- Neurosurgery
- Critical Care Medicine
Context:
- Space occupying strokes, a complication of ischemic supratentorial infarctions (1-10% of cases), lead to severe secondary brain damage.
- Brain edema and elevated intracranial pressure (ICP) are the primary drivers of high mortality and morbidity in these patients.
- Effective management of brain edema and ICP is crucial for improving patient outcomes.
Purpose:
- To provide surgeon-centered recommendations on the indication and timing of decompressive craniectomy (DC).
- To review current treatment strategies for managing space occupying strokes and associated intracranial pressure.
- To guide neurosurgical decision-making in complex stroke cases.
Summary:
- Extensive space occupying strokes necessitate ICP management, often involving decompressive craniectomy (DC) when conservative measures are insufficient.
- DC aims to alleviate elevated intracranial pressure, thereby mitigating secondary brain injury.
- This review focuses on the surgical perspective for DC in both supratentorial and infratentorial infarctions.
Impact:
- Offers evidence-based guidance for neurosurgeons managing space occupying strokes.
- Aims to optimize the use of decompressive craniectomy, potentially reducing stroke-related mortality and morbidity.
- Contributes to the understanding of surgical interventions for severe ischemic stroke complications.
Related Concept Videos
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Increased Intracranial Pressure l: Introduction
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...

