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Is conventional hemodialysis enough to manage carbamazepine intoxication?
Alper Azak1, Gülay Koçak, Bülent Huddam
1Department of Nephrology, Ankara Education and Research Hospital, Ankara, Turkey. dralperazak@gmail.com
Abstract:
Hemodialysis (HD) is a technique that helps in the management of drug intoxications/overdoses - the most important point being the protein-binding rate of the molecules which have to be cleared. In cases where the drug is not bound to the proteins, conventional HD may be effective enough, but if the drug is highly bound to proteins then HD may be insufficient to be effective. Hemoperfusion and albumin dialysis are therefore appropriate alternatives. Herein we report a case of carbamazepine intoxication where conventional HD treatment was performed.
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