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Stem cell-based tissue engineering in veterinary orthopaedics.

Walter Brehm¹, Janina Burk, Uta Delling

¹Large Animal Clinic for Surgery, University of Leipzig, An den Tierkliniken 21, 04103, Leipzig, Germany, brehm@vetmed.uni-leipzig.de.

Cell and Tissue Research

|January 31, 2012

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No simple way to averaging out: Pooled mesenchymal stromal cells do not reflect average donor characteristics.

Regenerative therapy·2025

Regenerative veterinary medicine, particularly using mesenchymal stromal cells (MSC), is advancing rapidly. This field shows promise for treating orthopaedic injuries and disorders in animals, serving as a model for human medicine.

Area of Science:

Regenerative medicine
Veterinary orthopaedics
Biotechnology

Background:

Regenerative medicine is a rapidly advancing field with significant annual progress.
Collaboration between human and veterinary medical scientists drives pioneering innovations.
Animals serve as crucial models for human medicine, providing preclinical data.

Purpose of the Study:

To provide an overview of stem cell-based tissue engineering in veterinary orthopaedics.
To highlight past and current achievements in the field.
To discuss future perspectives and potential of regenerative therapies.

Main Methods:

Review of current literature and clinical practices in regenerative veterinary medicine.
Focus on mesenchymal stromal cells (MSC) for therapeutic applications.

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Last Updated: May 25, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots

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Analysis of MSC applications in orthopaedic conditions.

Main Results:

Mesenchymal stromal cells (MSC) are increasingly used in veterinary regenerative medicine.
MSC therapies are becoming routine for acute injuries and chronic disorders in animals.
Orthopaedic disorders are a primary focus for MSC therapies in veterinary practice.

Conclusions:

Regenerative veterinary medicine, especially using MSC, holds significant scientific and clinical potential.
The veterinary field plays a vital role in advancing regenerative medicine through animal models.
Stem cell-based tissue engineering offers promising future applications for veterinary orthopaedics.