Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cocaine-induced hepatonephrotoxicity: a case report.

G P Gubbins1, R M Schiffman, R S Alapati

  • 1Division of Gastroenterology, Henry Ford Hospital, Detroit, MI 48202.

Henry Ford Hospital Medical Journal
|January 1, 1990
PubMed
Summary

Cocaine use can cause acute liver and kidney damage (hepatonephrotoxicity) in humans. This case report details a reversible instance linked to recreational drug use, exploring potential toxic mechanisms.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy by hyperactivating Wnt/β-catenin signaling.

Oncogene·2017
Same author

Gut permeability and mucosal inflammation: bad, good or context dependent.

Mucosal immunology·2017
Same author

RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment.

Oncogene·2016
Same author

Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival.

Oncogene·2016
Same author

MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.

Oncogene·2016
Same author

Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.

Oncogene·2015

Area of Science:

  • Toxicology
  • Hepatology
  • Nephrology

Background:

  • Cocaine-induced hepatotoxicity is established in animal models.
  • Human cases of cocaine-induced liver injury are infrequently reported.
  • The association of cocaine use with rhabdomyolysis and renal failure is more recognized.