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Cocaine-induced hepatonephrotoxicity: a case report
G P Gubbins1, R M Schiffman, R S Alapati
1Division of Gastroenterology, Henry Ford Hospital, Detroit, MI 48202.
Henry Ford Hospital Medical Journal
|January 1, 1990
Abstract:
Hepatotoxicity due to cocaine has been well described in animal models. There are few reports on cocaine-induced hepatic injury in humans; however, its link to rhabdomyolysis and renal failure is better known. We report a case of reversible acute hepatonephrotoxicity associated with recreational cocaine use. The proposed mechanisms responsible for its hepatic and renal toxicity are reviewed.