Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Safety and outcomes of laparoscopic bile duct exploration: a UK-wide multi-centre study (R-ALiCE).

Surgical endoscopy·2026
Same author

Cradle Compression During Normothermic Machine Perfusion of Livers: Struggling Under the Weight of Expectation?

Transplantation·2026
Same author

Safety and Outcomes of Laparoscopic Common Bile Duct Exploration in Elderly Patients: A Retrospective Comparative Cohort Study From a High-Volume Specialist Centre.

Journal of hepato-biliary-pancreatic sciences·2026
Same author

Integrating ERCP Within UK Higher Surgical Training: A Structured, Curriculum-Embedded Model.

Surgical laparoscopy, endoscopy & percutaneous techniques·2026
Same author

Correction to: Safety and outcomes of laparoscopic bile duct exploration: a UK-wide multi-centre study (R-ALiCE).

Surgical endoscopy·2026
Same author

Safety and outcomes of laparoscopic bile duct exploration: a UK-wide multi-centre study (R-ALiCE).

Surgical endoscopy·2026

Related Experiment Video

Updated: May 25, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Acute appendicitis with unusual dual pathology.

Georgina E Riddiough1, Imran Bhatti, David A Ratliff

  • 1Department of Vascular Surgery, Northampton General Hospital, Cliftonville, Northampton NN1 5BD, United Kingdom.

International Journal of Surgery Case Reports
|January 31, 2012
PubMed
Summary

Meckel's diverticulum, a rare congenital condition, can cause complex intestinal obstructions like intussusception. This case highlights the importance of considering Meckel's diverticulum in surgical diagnoses, even when not inflamed.

Keywords:
Acute appendicitisGeneral surgeryMeckel's diverticulumPaediatric surgery

Related Experiment Videos

Last Updated: May 25, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Area of Science:

  • Gastroenterology
  • Surgical Pathology
  • Congenital Abnormalities

Background:

  • Meckel's diverticulum is a rare congenital anomaly resulting from persistent vitelline duct, affecting 1-3% of the population.
  • Its varied clinical presentations, including bleeding, obstruction, and inflammation, often complicate diagnosis.

Purpose of the Study:

  • To report a case of small bowel obstruction secondary to an inverted Meckel's diverticulum causing intussusception.
  • To discuss the diagnostic challenges and implications for surgical practice.

Main Methods:

  • Case report detailing a patient with acute appendicitis and subsequent persistent postoperative small bowel obstruction.
  • Surgical exploration revealed an intussuscepted, non-inflamed Meckel's diverticulum as the cause.

Main Results:

  • An inverted Meckel's diverticulum was identified as the cause of intussusception and small bowel obstruction.
  • Obstruction due to intussusception from Meckel's diverticulum is an uncommon but significant cause of complex clinical presentations.

Conclusions:

  • Intestinal obstruction in Meckel's diverticulum can manifest as volvulus, intussusception, or hernia incarceration.
  • The case prompts consideration for routine bowel examination for Meckel's diverticulum during laparoscopy due to its potential for obscure presentations.