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Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case

Suneth Karunarathne1, Yapa Udayakumara, Harshini Fernando

  • 1Ward 49, National Hospital of Sri Lanka, Regent Street, Colombo 08, Sri Lanka. suneth871@gmail.com.

Journal of Medical Case Reports
|February 1, 2012
PubMed

Insights

This case report details the first instance of post-infectious cerebellitis in a patient with confirmed Epstein-Barr and dengue viral infections. The patient recovered fully with supportive care, highlighting diagnostic considerations for cerebellitis.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Post-infectious cerebellitis is an acute cerebellar inflammation, often seen in children after viral infections like Epstein-Barr virus.
  • It typically presents with sudden onset dysarthria and ataxia.
  • This condition is rarely reported in adults, especially with co-occurring viral infections.

Purpose of the Study:

  • To report the first case of post-infectious cerebellitis in a patient with confirmed co-infection of dengue and Epstein-Barr virus.
  • To discuss the clinical presentation, diagnostic findings, and management of this rare neurological complication.

Main Methods:

  • A case study of a 43-year-old male presenting with acute febrile illness and thrombocytopenia.
  • Diagnostic workup included serological tests for dengue and Epstein-Barr virus, cerebrospinal fluid analysis, and MRI.
  • The patient received supportive care for viral meningoencephalitis.

Main Results:

  • The patient presented with symptoms of dengue fever, later developing dysarthria, ataxia, and cerebellar signs.
  • Serological tests confirmed active Epstein-Barr virus and dengue infection.
  • Cerebrospinal fluid analysis indicated viral meningoencephalitis, and MRI findings were consistent with post-viral cerebellitis.

Conclusions:

  • This is the first reported case of post-infectious cerebellitis associated with concurrent dengue and Epstein-Barr viral infections.
  • The case underscores the importance of considering multiple etiologies in complex presentations.
  • Successful management with supportive care indicates a good prognosis for uncomplicated cerebellitis.
Abstract

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