Related Experiment Video
Updated: May 25, 2026

An Intact Pericardium Ischemic Rodent Model
Published on: September 2, 2021
Pericardial diseases
Insights
The pericardium, a protective sac around the heart, can become inflamed or fill with fluid, leading to various heart conditions. Recent imaging advances improve diagnosis and treatment of pericardial diseases.
Area of Science:
- Cardiology
- Anatomy
- Pathophysiology
Background:
- The pericardium is a vital structure enclosing the heart, facilitating its function and maintaining its position.
- Pericardial abnormalities can present as diverse cardiac and systemic diseases.
- Injury to the pericardium often results in inflammation and fluid accumulation.
Purpose of the Study:
- To present the anatomy and physiology of the pericardium.
- To outline the clinical approach for diagnosing and treating pericardial diseases.
Main Methods:
- Review of anatomical and physiological principles of the pericardium.
- Discussion of diagnostic imaging advancements.
- Outline of clinical diagnostic and therapeutic strategies.
Main Results:
- Understanding pericardial anatomy and physiology is crucial for recognizing disease.
- Inflammation and fluid accumulation are common responses to pericardial injury.
- Advanced imaging techniques enhance diagnostic accuracy.
Conclusions:
- Pericardial diseases encompass a range of conditions affecting cardiac and systemic health.
- A systematic clinical approach, aided by modern imaging, is essential for effective diagnosis and management.
- Further research into pericardial pathophysiology can lead to improved patient outcomes.
Abstract:
The pericardium provides an enclosed lubricated space for the beating heart and functions to fix the heart in the chest cavity relative to adjacent organs. Pericardial pathophysiology is often manifested in a spectrum of distinct cardiac and systemic disease states. The pericardial response to injury typically involves a spectrum of inflammation with both acute and chronic features and/or fluid accumulation. Recent advances in imaging methods have refined the diagnosis and therapy of pericardial disease. This article presents the anatomy and physiology of pericardial disease and the clinical approach for diagnosis and treatment.
Related Concept Videos
Pericarditis I: Introduction
Pericarditis III: Medical Management
Pericarditis II: Clinical Features and Diagnostic Tests
Cardiomyopathy I: Introduction and Classification
Rheumatic Heart Disease I: Introduction
Pericarditis IV: Nursing Management
