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Maternal smoking during pregnancy and primary headache in school-aged children: a cohort study

Carlos E Fabbri1, Marco A Barbieri, Antônio M Silva

  • 1University of São Paulo, São Paulo, Brazil.

Cephalalgia : an International Journal of Headache
|February 1, 2012
PubMed

Insights

Maternal smoking during pregnancy is linked to a higher prevalence of primary headaches in children aged 7-11. This association was observed across two prospective cohorts, suggesting a potential contribution of prenatal smoke exposure to childhood headaches.

Area of Science:

  • Pediatrics
  • Neuroscience
  • Public Health

Background:

  • The relationship between maternal smoking during pregnancy and offspring headache is not well-established.
  • Childhood headaches represent a significant health concern with potential long-term impacts.

Purpose of the Study:

  • To investigate the association between maternal smoking during pregnancy and the occurrence of primary headaches in children.
  • To analyze this association in two distinct prospective cohorts.

Main Methods:

  • Two prospective cohorts (Ribeirão Preto, n=869; São Luís, n=805) of children aged 7-11 years were studied.
  • Maternal smoking data were collected at birth; primary headache was defined by symptom reporting.
  • Data were analyzed considering maternal reports and children's self-reports.

Main Results:

  • Headache prevalence varied between cohorts and reporters (mothers vs. children).
  • Agreement between maternal and child headache reports was poor.
  • Maternal smoking of ≥10 cigarettes/day during pregnancy was associated with higher primary headache prevalence in offspring, particularly in the Ribeirão Preto cohort.

Conclusions:

  • Maternal smoking during pregnancy is associated with an increased risk of primary headaches in children aged 7-11 years.
  • Despite discrepancies in reporting, the findings suggest prenatal smoke exposure may contribute to childhood headaches.
Abstract

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