Related Experiment Video
Updated: May 25, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Alcoholism and cellular vulnerability in different brain regions
Sandra Skuja1, Valerija Groma, Liene Smane
1Institute of Anatomy and Anthropology, Riga Stradins University, Riga, Latvia. sandra.skuja@gmail.com
Abstract:
Alcohol-induced damage causes dysfunction of selected brain regions. Multidisciplinary studies have provided an extensive description of changes observed in neurons and glia following alcohol consumption. In this study the authors have elucidated preferential cellular vulnerability in three different brain regions. Autopsy material of the prefrontal cortex, striatum, and substantia nigra obtained from the brain tissue of alcoholic subjects was used in this study. We found that dendritic tree and astroglial damage is irreversible, while neuronal somata and most axons do not display irreversible changes.
More Related Videos
Related Concept Videos
CNS Depressants: Alcohol and Nicotine
Alzheimer Disease ll: Pathophysiology
Alzheimer Disease l: Introduction
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Hepatic Encephalopathy
Dementia l: Introduction

