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Antibacterial potential of benzoate and phenylethanoid derivatives isolated from Acanthus ilicifolius L. leaf
S Ravikumar1, M Raja, M Gnanadesigan
1School of Marine Sciences, Department of Oceanography and Coastal Area Studies, Alagappa University, Thondi Campus, Thondi 623409, Ramanathapuram District, Tamil Nadu, India. ravibiotech201321@gmail.com
Abstract:
The antibacterial activities of column chromatography fractions of n-hexane, benzene, chloroform, acetone, ethanol and water extracts from Acanthus ilicifolius were tested against 24 bacterial pathogens. The antibacterial activity was performed using agar diffusion method. Most active fractions were further investigated through UV-Vis, (13)C, (1)H-NMR, FT-IR for the structural elucidation. The antibacterial activity of the extracts was identified as 6-hydroxy-benzoxazolinone, (Z)-4-coumaric acid 4-O-β-D-glucopyranoside and 3,5-dimethoxy-4-hydroxy methyl benzoate.
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