Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

3D Printed Flexible Piezoelectric Sensors for Integrated Hybrid Electronics.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

33 Unresolved Questions in Nanoscience and Nanotechnology.

ACS nano·2025
Same author

3D printed anisotropic tissue simulants with embedded fluid capsules for medical simulation and training.

Science advances·2025
Same author

3D vector field-guided toolpathing for 3D bioprinting.

Communications engineering·2025
Same author

3D-Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury.

Advanced healthcare materials·2025
Same author

3D Printed Organisms Enabled by Aspiration-Assisted Adaptive Strategies.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2024

Related Experiment Video

Updated: May 25, 2026

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
10:50

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Published on: July 16, 2018

Biomimetic peptide nanosensors.

Yue Cui1, Sang N Kim, Rajesh R Naik

  • 1Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, USA.

Accounts of Chemical Research
|February 2, 2012
PubMed
Summary

Researchers developed peptide nanosensors for highly sensitive and selective detection of biochemical targets. These novel "nanoelectronic noses" show promise for detecting chemical warfare agents and diagnosing diseases from breath.

More Related Videos

CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics
04:33

CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics

Published on: December 8, 2023

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

Related Experiment Videos

Last Updated: May 25, 2026

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
10:50

Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics

Published on: July 16, 2018

CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics
04:33

CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics

Published on: December 8, 2023

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

Area of Science:

  • Nanotechnology
  • Biochemistry
  • Sensor Technology

Background:

  • Nanomaterials offer high sensitivity due to their large surface-to-volume ratios.
  • Peptides provide selective recognition capabilities due to their diverse chemical structures.
  • Developing integrated nanosensor platforms is crucial for advanced biochemical detection.

Purpose of the Study:

  • To explore the integration of peptides with nanomaterials for creating selective nanosensors.
  • To address challenges in rational peptide design, nanomaterial selection, and hybrid assembly.
  • To investigate the role of molecular modeling in understanding sensor mechanisms and performance.

Main Methods:

  • Utilized natural or phage-displayed peptide sequences as recognition elements.
  • Employed various nanomaterials like nanowires, graphene, and carbon nanotubes.
  • Assembled peptide-nanomaterial hybrids using surface functionalization and self-assembly techniques.
  • Applied molecular modeling to analyze nanostructure and detection mechanisms.

Main Results:

  • Demonstrated peptide nanosensors capable of distinguishing complex vapor mixtures.
  • Achieved high sensitivity (parts-per-billion levels) in detecting chemical warfare agents.
  • Validated the effectiveness of molecular modeling in elucidating sensor behavior.

Conclusions:

  • Developed a novel platform for highly sensitive and selective biochemical detection using peptide-functionalized nanomaterials.
  • These "nanoelectronic noses" offer a promising approach for real-time monitoring and diagnostics.
  • Future applications include disease detection through breath analysis in biomedicine.