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Updated: May 25, 2026
09:49
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
Update on gastrointestinal radiopharmaceuticals and dosimetry estimates
1Department of Radiology, Temple University School of Medicine, Philadelphia, PA 19140, USA. LKnight@temple.edu
Seminars in Nuclear Medicine
|February 2, 2012
Summary
Gastric emptying studies require reliable radiolabeled meals. This research evaluates alternative meals and provides updated radiation dosimetry for various patient groups, aiding clinical practice.
Area of Science:
- Gastroenterology and Nuclear Medicine
Background:
- Scintigraphy with radiolabeled meals is the gold standard for gastric emptying measurement.
- Standardized radiolabeled solid meals are increasingly adopted, but alternatives are needed.
- Previous evaluations of alternative meals were limited in scope.
Purpose of the Study:
- To assess the suitability of alternative radiolabeled meals for gastric emptying studies.
- To provide updated radiation dosimetry for these alternative meals in diverse patient populations.
Main Methods:
- Evaluation of several radiolabeled meals for radiolabel stability.
- Calculation of radiation dosimetry for adult males and females.
- Consideration of normal and abnormal gastrointestinal transit times.
Main Results:
- Several alternative radiolabeled meals demonstrated stability.
- Updated radiation dosimetry data were calculated for various scenarios.
Conclusions:
- Alternative radiolabeled meals show promise for gastric emptying measurements.
- Updated dosimetry supports the safe use of these meals in clinical settings.
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