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Updated: May 25, 2026

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Overview of animal models of asthma
1Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland, USA.
Abstract:
Asthma is an inflammatory disease characterized by airways obstruction, airways hyperresponsiveness, excessive mucous secretion and cough. Guinea pig airways display many anatomical, physiological and pharmacological attributes of human airways, making this species ideal for modeling the asthmatic condition. This unit provides an overview of animal models of asthma, including definitions, descriptions of available animal models, and discussion of numerous critical issues to consider before designing a model to study this complex disease.
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