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Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions01:15

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions

PK–PD modeling has significantly influenced FDA regulatory decisions, particularly drug approval, dosage optimization, and labeling. These models integrate pharmacokinetics (PK) and pharmacodynamics (PD) to predict drug behavior and effects, aiding in optimizing dosing regimens and enhancing the probability of clinical trial success.One notable example is Nesiritide (Natrecor®), a recombinant human brain natriuretic peptide for treating acute decompensated congestive heart failure (CHF).
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
SBAR I: Understanding the Concept01:29

SBAR I: Understanding the Concept

Effective communication among healthcare professionals during hand-off reporting is essential to delivering safe and continuous patient care. Common professional interactions include reports to healthcare team members, hand-off, and transfer reports. Nurses routinely report information to other healthcare team members and also urgently contact healthcare providers to report changes in patient status.
Standardized methods of communication have been developed to ensure that information is...

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Related Experiment Video

Updated: May 25, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

The NSABB recommendations: rationale, impact, and implications.

Paul S Keim1

  • 1National Science Advisory Board for Biosecurity, Office of Biotechnology Activities, National Institutes of Health, Bethesda, Maryland, USA. paul.keim@nau.edu

Mbio
|February 2, 2012
PubMed
Summary
This summary is machine-generated.

The National Science Advisory Board for Biosecurity recommended restricting H5N1 influenza research. This decision prioritized public health over potential negative consequences of mammal-to-mammal transmission studies.

Related Experiment Videos

Last Updated: May 25, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

Area of Science:

  • Virology
  • Public Health Policy
  • Biosecurity

Background:

  • Avian H5N1 influenza virus poses a pandemic threat.
  • Laboratory studies aim to understand virus transmission.
  • Dual Use Research of Concern (DURC) requires careful evaluation.

Purpose of the Study:

  • To evaluate the biosecurity risks of H5N1 influenza research.
  • To determine if specific H5N1 studies constitute DURC.
  • To provide recommendations on managing high-consequence research.

Main Methods:

  • The National Science Advisory Board for Biosecurity (NSABB) convened experts.
  • Reviewed scientific papers on laboratory-adapted H5N1 influenza.
  • Assessed research against established DURC criteria and policies.

Main Results:

  • NSABB recommended restricting content of two H5N1 papers.
  • Potential negative consequences outweighed research benefits.
  • The research involved avian H5N1 adaptation for mammal-to-mammal transmission.

Conclusions:

  • NSABB's recommendation highlights the importance of biosecurity in research.
  • Careful consideration of dual use risks is crucial for public health.
  • Governmental bodies play a key role in managing high-risk scientific findings.