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Prevalence and predictors of low vitamin D concentrations in urban Canadian toddlers
Jonathon L Maguire1, Catherine S Birken, Deborah L O'Connor
1Department of Pediatrics, St Michael's Hospital;
Insights
Many Canadian toddlers have low vitamin D levels, with higher body mass index (BMI) and lower cow
Area of Science:
- Pediatric Nutrition
- Nutritional Biochemistry
- Public Health
Background:
- Vitamin D is crucial for bone health and immune function in children.
- Low vitamin D concentrations (hypovitaminosis D) are a growing concern in pediatric populations globally.
- Urban environments and lifestyle factors may influence vitamin D status in toddlers.
Purpose of the Study:
- To assess the prevalence of vitamin D deficiency in healthy two-year-old children in Toronto, Canada.
- To investigate the association between body mass index (BMI) and cow's milk intake with vitamin D status.
- To identify potential modifiable risk factors for low vitamin D in urban toddlers.
Main Methods:
- A cross-sectional study involving 91 healthy children aged 24-30 months in Toronto, Ontario.
- Dietary intake, including cow's milk consumption, was assessed via questionnaire.
- Vitamin D status was determined by measuring 25-hydroxyvitamin D concentrations, with low levels defined as <50 nmol/L or <75 nmol/L.
Main Results:
- The prevalence of low vitamin D (<50 nmol/L) was 32%, and <75 nmol/L was 82%.
- Higher BMI was associated with an increased odds of low vitamin D (<50 nmol/L).
- Each additional daily cup of cow's milk intake was associated with a decreased odds of low vitamin D (<50 nmol/L).
Conclusions:
- A significant proportion of urban Canadian toddlers exhibit insufficient vitamin D levels.
- Lower cow's milk intake and higher BMI are associated with reduced vitamin D status in this cohort.
- The findings highlight the need for targeted interventions to improve vitamin D status in Canadian toddlers.
Objectives:
To determine the prevalence of low vitamin D concentrations in a cohort of healthy two-year-old children living in a large Canadian city, and to explore whether body mass index (BMI) and cow's milk intake are associated with low vitamin D concentrations.
Methods:
A cross-sectional study was performed on healthy two-year-old children attending a well-child visit in Toronto, Ontario (latitude 43.4°N). Dietary exposures were measured by questionnaire. The primary outcome was the prevalence of low vitamin D concentrations (25-hydroxyvitamin D concentration of lower than 50 nmol/L or lower than 75 nmol/L).
Results:
A total of 91 healthy children 24 to 30 months of age were recruited between November 2007 and May 2008. The prevalence of low vitamin D concentrations (lower than 50 nmol/L) was 32% (29 of 92, 95% CI 22% to 42%) and the prevalence of vitamin D concentrations of lower than 75 nmol/L was 82% (75 of 91, 95% CI 73% to 89%). Using multivariable logistic regression, the odds of vitamin D concentrations being lower than 50 nmol/L decreased by 0.44 (95% CI 0.2 to 0.96) for each additional cup of cow's milk intake per day and increased by 1.2 to 2.6 per unit BMI depending on BMI level (P=0.07).
Conclusions:
A total of 30% to 80% of toddlers in the present study's urban Canadian setting demonstrated low vitamin D concentrations - the highest prevalence of low vitamin D in toddlers outside of Alaska. Modifiable factors associated with low vitamin D were lower cow's milk intake and higher BMI. The vitamin D status of toddlers in urban Canada may require specific attention.
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