Related Experiment Video
Updated: May 25, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
[Alternate-day oral tadalafil for erectile dysfunction with no successful intercourse at the baseline]
Qiang Du1, Zheng-tao Li, Xin Xing
1Center of Reproductive Medicine, Shengjing Hospital, China Medical University, Shenyang, Liaoning 110003, China.
Objective:
To summarize the experience in the treatment of erectile dysfunction (ED) with no successful intercourse at the baseline with tadalafil.
Methods:
We retrospectively analyzed 21 cases of ED with no successful intercourse at the baseline treated with tadalafil on alternate days combined with sex guidance.
Results:
After 4 weeks of tadalafil treatment, 19 of the patients achieved successful sexual intercourse, and the IIEF-5 score was remarkably improved as compared with pre-medication (3.24 +/- 1.55 vs 18.95 +/- 3.02, P<0.0001). Mild adverse reactions were observed in 6 cases, including 2 cases of mild headache and 4 cases of facial blush.
Conclusion:
Tadalafil on alternate days combined with sex guidance can significantly improve ED with no successful intercourse at the baseline.
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