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Published on: January 12, 2018
The Actim Partus test to predict pre-term birth in asymptomatic high-risk women
H Khambay1, L A Bolt, M Chandiramani
1Women's Health Academic Centre, King's Health Partners, Kings College London, Maternal and Fetal Research Unit, Division of Reproduction and Endocrinology, St Thomas' Hospital, London, United Kingdom. hasmeet.khambay@kcl.ac.uk
Abstract:
The Actim Partus test has been shown to be a useful predictor of pre-term birth in symptomatic women, but limited research has been carried out in high-risk asymptomatic women. This is a pilot study to evaluate the use of this test as a direct comparator with the fetal fibronectin test. All asymptomatic high-risk women attending a pre-term surveillance clinic over a 9-month period, took an Actim Partus and fetal fibronectin test, between 23(+0)-24(+6) weeks' gestation. A total of 45 women were eligible. The positive and negative predictive values of the Actim Partus test for delivery at ≤ 37 weeks' gestation were 0% and 70%, respectively, compared with the fetal fibronectin test, with values of 67% and 79%, respectively. It was concluded that the Actim Partus test did not perform well as a predictor of pre-term birth in high-risk asymptomatic women.
