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Updated: May 25, 2026

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Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Published on: September 20, 2021
A case series: herpes simplex virus as an occupational hazard
William D Browning1, James P McCarthy
1Indiana University School of Dentistry, Indianapolis, IN, USA.
Summary
Herpes labialis infections pose a significant risk to dental professionals. This study reviews herpes simplex virus type 1 (HSV-1) transmission and provides evidence-based strategies to protect dental teams from cross-contamination.
Area of Science:
- Dentistry
- Infectious Diseases
- Public Health
Background:
- Herpes labialis infections are common and pose a serious risk to dental professionals.
- Understanding the transmission of herpes simplex virus type 1 (HSV-1) is crucial for dental practice.
Observation:
- HSV-1 is highly contagious and transmissible, particularly through aerosols.
- Case histories illustrate the impact of HSV-1 sequelae on dental teams.
- Aerosol transmission necessitates inclusion in universal precautions.
Findings:
- Limiting treatment of active herpes labialis lesions to urgent care is recommended.
- Treating active HSV-1 lesions can reduce healing time.
- Evidence-based methods protect dental teams and patients from cross-contamination.
Implications:
- Implementing robust protocols can control the risk of herpes infection spread in dental settings.
- Dental practitioners can take positive steps to prevent herpes transmission.
- Enhanced universal precautions, including aerosol protection, are vital.
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