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Updated: May 25, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Social cognition and global functioning in bipolar disorder.

Guillermo Lahera¹, Salvador Ruiz-Murugarren, Paloma Iglesias

¹Principe de Asturias University Hospital, University of Alcala, Madrid, Spain. guillermo.lahera@uah.es

The Journal of Nervous and Mental Disease

|February 3, 2012

Summary

Impaired social cognition affects the daily functioning of bipolar disorder patients. Addressing these cognitive challenges may improve overall clinical outcomes and reduce the gap between illness and daily life.

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Last Updated: May 25, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Area of Science:

Psychiatry and Behavioral Sciences
Neuroscience
Clinical Psychology

Background:

Bipolar disorder (BD) is a mood disorder characterized by significant functional impairments.
The relationship between cognitive deficits and functional outcomes in euthymic BD patients requires further elucidation.
Social cognition deficits have been implicated in various psychiatric conditions, but their specific role in BD functioning is less understood.

Purpose of the Study:

To investigate the role of social cognition in the global functioning of euthymic bipolar disorder patients.
To compare social cognition, general cognition, and clinical variables between high and low global functioning groups in bipolar disorder.

Main Methods:

Thirty-nine euthymic outpatients with bipolar disorder type I or II were assessed.
Participants were divided into high (n=19) and low (n=20) global functioning groups.
Evaluated measures included verbal and nonverbal social cognition (Faux pas test, Facial Emotion Recognition test), sustained attention, and executive function.

Main Results:

The low-functioning group exhibited significant impairments in both verbal and nonverbal social cognition compared to the high-functioning group.
Both bipolar disorder groups demonstrated significant deficits in facial emotion recognition when compared to healthy volunteers.
Social cognition deficits were more pronounced in individuals with lower global functioning.

Conclusions:

Social cognition plays a significant role in the clinical-functional gap observed in euthymic bipolar disorder patients.
Targeting social cognition deficits may be a crucial therapeutic strategy to improve functional outcomes in bipolar disorder.
These findings highlight the importance of assessing and treating social cognition impairments for comprehensive bipolar disorder management.