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Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

Smaller platelet volumes associated with vascular malformations

Marvin H Klapman1, Valentina B Sosa, Gail F Mattson-Gates

  • 1Dermatology Clinic and Vascular Birthmark Service Southern California Kaiser Permanente, Pasadena, CA 91107, USA. marvinklapman@gmail.com

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|February 3, 2012
PubMed

Various parameters in 91 adult participants with vascular malformations and 91 controls were studied. The mean of the participants' platelet volumes was 8.5 fL and that of their controls was 9.1 (P < .001). The mean of the participants' platelet mass was 2145 µL/L of blood and that of their controls was 2351 (P = .006). The other parameters studied were not significantly different than the controls. It is suggested that the lower platelet volume might be related to a compensatory mechanism to keep the total body platelet mass stable despite the increased vasculature.

Keywords:
platelet functionthrombosisvascular disease

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