Related Experiment Video

Updated: May 25, 2026

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

Predictors of local venous complications resulting from electrophysiological procedures

Abolfath Alizadeh1, Amir Hosein Yazdi, Mohammad Kafi

  • 1Department of Pacemaker and Electrophysiology, Rajaie Cardiovascular Medical Center, Iran University of Medical Sciences, Tehran, Iran. Alizadeh_73@yahoo.com

Cardiology Journal
|February 3, 2012
PubMed

Insights

Heparinization during electrophysiological procedures reduced in situ thrombosis, especially with single venous line cannulation and in women. Deep vein thrombosis was not observed, suggesting heparin may not be necessary for right-sided procedures.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Medical Device Technology

Background:

  • Radiofrequency catheter ablation (RFCA) carries a 0.6% risk of thromboembolic complications.
  • Multiple venous sheaths are often required for electrophysiological studies and RFCA, necessitating placement in a single femoral vein.
  • The safety of single venous line cannulation for multiple sheaths requires further investigation.

Purpose of the Study:

  • To evaluate the safety of placing multiple venous sheaths via a single venous line.
  • To assess the effect of heparinization on deep vein thrombosis (DVT) and in situ thrombosis during these procedures.

Main Methods:

  • A randomized clinical trial involving 200 patients.
  • Comparison of single venous line cannulation versus separate venous sheath placement.
  • Analysis of heparinization protocols and their impact on thrombosis rates.

Main Results:

  • No cases of deep vein thrombosis (DVT) were observed.
  • Heparinization significantly reduced in situ thrombosis (28% vs. 11%, p=0.04).
  • Single venous line cannulation showed a higher in situ thrombosis rate (16% vs. 6% with heparin, p=0.1; 38% vs. 18% without heparin, p=0.04).
  • Women had a significantly higher rate of in situ thrombosis than men (26% vs. 11%, p=0.01).

Conclusions:

  • Heparinization is not essential for right-sided electrophysiological procedures due to low DVT risk.
  • In situ thrombosis is a minor complication manageable with heparinization, particularly for single venous line cannulation and in women.
  • Advanced age did not influence thrombosis rates.
Abstract

More Related Videos

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein05:51

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein

Published on: January 13, 2026

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...