Related Experiment Video
Updated: May 25, 2026

Cardiac Stress Test Induced by Dobutamine and Monitored by Cardiac Catheterization in Mice
Published on: February 10, 2013
Progressive bradycardia with increasing doses of dobutamine leading to stress echo interruption
Maria Olszowska1, Piotr Musiałek, Rafał Drwiła
1Department of Cardiac and Vascular Disease, Institute of Cardiology, Collegium Medicum of the Jagiellonian University, Krakow, Poland. molszowska@szpitaljp2.krakow.pl
Insights
Dobutamine stress testing can evaluate coronary artery disease. This study details a rare case where increasing dobutamine doses caused a progressive bradycardia, leading to test interruption.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Dobutamine stress testing is a key non-invasive diagnostic tool.
- It is crucial for patients with coronary artery disease who cannot exercise.
- Assessing cardiac function under stress is vital in clinical practice.
Abstract:
Dobutamine stress testing is an important non-invasive method for evaluating patients with known or suspected coronary artery disease who are unable to adequately exercise. We present a case of a paradoxical, progressive bradycardia occurring with increasing doses of dobutamine that resulted in stress test interruption.
Related Concept Videos
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Cardiomyopathy II: Dilated Cardiomyopathy
Decreased pulse rate
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with bradycardia...
Heart Failure Drugs: β-Blockers
Cardiomyopathy IV: Restrictive Cardiomyopathy
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
