Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Adrenergic Neurons: Neurotransmission

Adrenergic Neurons: Neurotransmission

Postganglionic sympathetic fibers (except those supplying the sweat glands) releasing noradrenaline or norepinephrine are called noradrenergic or adrenergic neurons. Noradrenaline, dopamine, adrenaline, or epinephrine are collectively called "catecholamines" as they contain a catechol moiety and an amine side chain. The five stages of neurotransmitter release involve their synthesis, storage, release, reuptake and metabolism.
Synthesis: Catecholamine synthesis requires tyrosine, which is taken...

Neurotransmitters

Neurotransmitters

Neurotransmitters play a crucial role in the communication between neurons in the autonomic nervous system. Neurons in the autonomic nervous system can be cholinergic or adrenergic depending on the neurotransmitters synthesized. Cholinergic neurons use acetylcholine as their primary neurotransmitter. This includes all the preganglionic fibers of the sympathetic and pre- and postganglionic fibers of the parasympathetic nervous systems. In addition, neurons of the somatic nervous system also use...

Cranial Part of Parasympathetic Division

Cranial Part of Parasympathetic Division

The cranial part of the parasympathetic division plays a crucial role in regulating the visceral functions of the head and specific structures in the neck, thoracic, and abdominopelvic cavities. Preganglionic fibers of the parasympathetic division exit the brain through cranial nerves III (oculomotor), VII (facial), IX (glossopharyngeal), and X (vagus), delivering parasympathetic output to the respective visceral structures.
The vagus nerve (cranial nerve X) alone accounts for approximately 75...

Olfactory Receptors: Location and Structure

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...

Regulation of Food Intake

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...

Neurotransmitters

Neurotransmitters

Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Research abstracts presented at the 46th annual scientific session of the Western Society of Allergy, Asthma, and Immunology.

Allergy and asthma proceedings·2017

Same author

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs.

The Journal of allergy and clinical immunology·2012

Same author

Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.

International archives of allergy and immunology·2012

Same author

Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper.

Allergy·2010

Same author

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen).

Allergy·2008

Same author

Unmet needs in asthma: Global Asthma Physician and Patient (GAPP) Survey: global adult findings.

Allergy·2007

Search research articles

Related Experiment Video

Updated: Jul 14, 2026

Intranasal Administration of CNS Therapeutics to Awake Mice

Intranasal Administration of CNS Therapeutics to Awake Mice

Published on: April 8, 2013

Neuropeptides and nasal secretion.

J N Baraniuk¹, M A Kaliner

¹National Heart and Lung Institute, London, England.

The Journal of Allergy and Clinical Immunology

|October 1, 1990

Summary

Autonomic nervous system neurotransmitters and neuropeptides control nasal secretions. Nonadrenergic, noncholinergic pathways offer longer-lasting effects than traditional cholinergic and adrenergic mechanisms in nasal responses.

Area of Science:

Neuroscience
Physiology

Background:

Autonomic nervous system neurotransmitters and neuropeptides regulate nasal secretion.
Cholinergic and adrenergic mechanisms have been considered primary, but nonadrenergic, noncholinergic (NANC) pathways may offer sustained effects.

Purpose of the Study:

To explore the role of various neurotransmitters and neuropeptides in nasal secretion and vasomotor rhinitis pathophysiology.
To investigate the contribution of sensory nerves and autonomic pathways to nasal vascular and glandular responses.

Main Methods:

Review of current research on neural control of nasal secretion.
Analysis of the functions of specific neuropeptides (e.g., CGRP, Substance P, NKA, VIP, NPY) in nasal physiology.
Examination of the interplay between sympathetic, parasympathetic, and sensory nervous systems in nasal function.

More Related Videos

An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization

An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization

Published on: August 10, 2013

Multi-Faceted Mass Spectrometric Investigation of Neuropeptides in Callinectes sapidus

Multi-Faceted Mass Spectrometric Investigation of Neuropeptides in Callinectes sapidus

Published on: May 31, 2022

Related Experiment Videos

Last Updated: Jul 14, 2026

Intranasal Administration of CNS Therapeutics to Awake Mice

Intranasal Administration of CNS Therapeutics to Awake Mice

Published on: April 8, 2013

An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization

An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization

Published on: August 10, 2013

Multi-Faceted Mass Spectrometric Investigation of Neuropeptides in Callinectes sapidus

Multi-Faceted Mass Spectrometric Investigation of Neuropeptides in Callinectes sapidus

Published on: May 31, 2022

Main Results:

Sensory nerve peptides (CGRP, Substance P, NKA) mediate vasodilation and plasma extravasation.
Substance P and gastrin-releasing peptide stimulate glandular secretion.
Vasoactive intestinal peptide modulates acetylcholine release and glandular secretion.
Neuropeptide Y acts as a vasoconstrictor in the sympathetic system.
Exaggerated neural influences may underlie vasomotor rhinitis.

Conclusions:

NANC pathways, involving sensory neuropeptides, play a significant role in nasal secretion and vascular control.
The integration of sympathetic, parasympathetic, and sensory systems is crucial for normal nasal function.
Dysregulation of these neural mechanisms, particularly an overactivity of defensive reflexes, is implicated in vasomotor rhinitis.