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Updated: May 25, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults in the UK: a consensus
Ann L N Chapman1, R Andrew Seaton, Mike A Cooper
1Department of Infection and Tropical Medicine, Royal Hallamshire Hospital, Sheffield, UK. ann.chapman@sth.nhs.uk
Abstract:
These good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) are an update to a previous consensus statement on OPAT in the UK published in 1998. They are based on previous national and international guidelines, but have been further developed through an extensive consultation process, and are underpinned by evidence from published literature on OPAT. They provide pragmatic guidance on the development and delivery of OPAT services, looking at all aspects of service design, care delivery, outcome monitoring and quality assurance, with the aim of ensuring that OPAT services provide high-quality, low-risk care, whatever the healthcare setting. They will provide a useful resource for teams developing new services, as well as a practical set of quality indicators for existing services.
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