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Prescription, Nonprescription and Orphan Drugs

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Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...
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Related Experiment Video

Updated: May 25, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Obstetrical opportunities: will pharmacy ever realize them?

Denise Ragland1, Gerald G Briggs, Mitzi Wasik

  • 1Department of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, USA. dragland@uams.edu

The Annals of Pharmacotherapy
|February 3, 2012
PubMed
Summary
This summary is machine-generated.

Pharmacists have limited involvement in obstetric pharmacotherapy, impacting pregnancy outcomes. Increased pharmacy practice in high-risk pregnancies can improve outcomes and is welcomed by physicians.

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Area of Science:

  • Pharmacology
  • Obstetrics
  • Women's Health

Background:

  • Current obstetric pharmacotherapy practices show limited engagement from the pharmacy profession.
  • This limited involvement may affect outcomes in pregnancies with complex conditions.

Purpose of the Study:

  • To document current obstetric pharmacy practices.
  • To propose changes for enhanced pharmacy involvement in obstetric pharmacotherapy.
  • To highlight the potential benefits of increased pharmacist participation in managing complicated pregnancies.

Main Methods:

  • Survey of the American College of Clinical Pharmacy Women's Health Practice and Research Network.
  • Analysis of existing clinical experience in obstetric pharmacotherapy.

Main Results:

  • The pharmacy profession demonstrates minimal participation in managing medications during pregnancy.
  • Physicians are likely receptive to greater pharmacist involvement in obstetric care.

Conclusions:

  • Enhanced pharmacist involvement in obstetric pharmacotherapy, particularly for complicated pregnancies, can significantly improve maternal and fetal outcomes.
  • The pharmacy profession should consider expanding its role in obstetric care to better serve patients and collaborating physicians.