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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

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Esophageal Achalasia01:27

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Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Pharynx01:20

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Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
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Related Experiment Video

Updated: May 25, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Parapharyngeal space synovial sarcoma.

L C Lina1, S Rosalind, R Philip

  • 1Department of Otorhinolaryngology, University Malaya, Kuala Lumpur, Malaysia. linalingchooi@yahoo.com

The Medical Journal of Malaysia
|February 4, 2012
PubMed
Summary
This summary is machine-generated.

Synovial sarcoma is a rare cancer. This case study highlights the aggressive nature of head and neck synovial sarcoma, showing disease recurrence even after aggressive treatment.

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Area of Science:

  • Oncology
  • Pathology

Background:

  • Synovial sarcoma is a rare soft tissue malignancy, typically affecting the lower extremities in young adults.
  • Head and neck synovial sarcomas are exceptionally rare and associated with a poor prognosis.

Observation:

  • A case of a 58-year-old female patient with left parapharyngeal synovial sarcoma is presented.
  • The tumor exhibited aggressive local and systemic spread patterns, complicating management.

Findings:

  • Despite complete surgical excision and adjuvant radiotherapy, the patient experienced disease recurrence.
  • This case underscores the challenges in achieving local-regional control for advanced synovial sarcoma.

Implications:

  • Aggressive multimodal therapy is crucial for managing this rare tumor.
  • Further research into novel therapeutic strategies is warranted to improve outcomes for synovial sarcoma, particularly in the head and neck region.