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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Updated: May 25, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Hairy nevus spilus: a case series.

Saurabh Singh1, Naresh Jain, Neena Khanna

  • 1Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

Pediatric Dermatology
|February 4, 2012
PubMed
Summary

Nevus spilus, a pigmented skin condition, can present with terminal hairs. This report details four cases of nevus spilus with hypertrichosis, emphasizing their benign nature.

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches
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Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches

Published on: May 20, 2022

Area of Science:

  • Dermatology
  • Dermatopathology

Background:

  • Nevus spilus, or speckled lentiginous nevus, is a congenital pigmented lesion.
  • While typically a cosmetic concern, rare malignant transformation to melanoma is possible.
  • Overlying hypertrichosis is an uncommon but reported feature of nevus spilus.

Purpose of the Study:

  • To report cases of nevus spilus with terminal hair growth.
  • To describe the clinical presentation and characteristics of these specific lesions.
  • To highlight the benign nature of these hairy nevus spilus variants.

Main Methods:

  • Case series reporting four patients with nevus spilus and hypertrichosis.
  • Clinical examination and photographic documentation of lesions.
  • Review of existing literature on nevus spilus and hypertrichosis.

Main Results:

  • Four cases of nevus spilus exhibiting significant overlying terminal hairs were identified.
  • The hypertrichosis predominantly arose from the background tan pigmentation of the nevus spilus.
  • No evidence of malignant change (melanoma) was observed in any of the reported cases.

Conclusions:

  • Nevus spilus can present with terminal hair growth, a feature not classically emphasized.
  • These hairy variants of nevus spilus appear to be benign.
  • Further investigation into the prevalence and etiology of hypertrichosis in nevus spilus is warranted.