Related Experiment Video

Updated: May 25, 2026

Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing
08:39

Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing

Published on: September 1, 2017

Novel ABCA-12 mutations leading to recessive congenital ichthyosis

Haley Peterson1, Sabra Lofgren, Samuel Bremmer

  • 1Department of Dermatology, Oregon Health & Science University, Portland, Oregon.

Pediatric Dermatology
|February 4, 2012
PubMed

More Related Videos

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Analysis of Zebrafish Larvae Skeletal Muscle Integrity with Evans Blue Dye07:34

Analysis of Zebrafish Larvae Skeletal Muscle Integrity with Evans Blue Dye

Published on: November 30, 2015

Related Concept Videos

Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...