Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
Autocrine Signaling01:01

Autocrine Signaling

Autocrine signaling is one of the many signaling mechanisms that function inside multicellular organisms to carry out intercellular communication. In this type of signaling mechanism, the same cell that secretes an extracellular signaling molecule also expresses the receptors to bind and respond to that signaling molecule.
Autocrine Signaling in Macrophages
Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. This process is well characterized in...
Autocrine Signaling01:01

Autocrine Signaling

Autocrine signaling is one of the many signaling mechanisms that function inside multicellular organisms to carry out intercellular communication. In this type of signaling mechanism, the same cell that secretes an extracellular signaling molecule also expresses the receptors to bind and respond to that signaling molecule.
Autocrine Signaling in Macrophages
Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. This process is well characterized in...
Microbial Corrosion01:24

Microbial Corrosion

Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shotgun metagenomic profiling reveals ecological and functional alterations of the oral microbiome in craniosynostosis.

Journal of oral microbiology·2026
Same author

Federated Learning in Endodontics: A Framework for Privacy-Preserving Multicentre Artificial Intelligence.

International dental journal·2026
Same author

Explainable Artificial Intelligence in Dentistry: A Systematic Review of Its Trust and Translation.

International dental journal·2026
Same author

In Vitro Single-Cell Transcriptomic Profiling of Cultured Stem Cells From Apical Papilla and Dental Pulp Stem Cells: Unveiling Cellular Heterogeneity.

International dental journal·2026
Same author

Explainable artificial intelligence in endodontics: Concepts, clinical applications, and future directions.

Journal of dentistry·2026
Same author

Denosumab Therapy in Dental Practice: Awareness, Risk Factors and Preventive Strategies.

Journal of osteoporosis·2026
Same journal

Protease-driven approaches for wound eschar debridement and biofilm disruption: current advances, future prospects, and limitations.

Critical reviews in microbiology·2026
Same journal

Environmental regulation of pathogenicity islands by nucleoid-associated proteins in bacteria.

Critical reviews in microbiology·2026
Same journal

New strains, new threats: the rise of atypical non-typhoidal <i>Salmonella</i> serovars and what it means for global health.

Critical reviews in microbiology·2026
Same journal

Tripartite warfare: decoding the cell-virus-virophage arms race.

Critical reviews in microbiology·2026
Same journal

Anti-<i>Candida albicans</i> natural products: convergent technologies revolutionizing discovery from bioactivity assessment to targeted mechanisms.

Critical reviews in microbiology·2026
Same journal

Retraction Notice.

Critical reviews in microbiology·2026
See all related articles

Related Experiment Video

Updated: May 25, 2026

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

Microbial chemical signaling: a current perspective.

H M H N Bandara1, O L T Lam, L J Jin

  • 1Oral Biosciences, Prince Philip Dental Hospital, 34, Hospital Road, Sai Ying Pun, Hong Kong.

Critical Reviews in Microbiology
|February 4, 2012
PubMed
Summary
This summary is machine-generated.

Microbial communication, known as quorum sensing, uses signal molecules to coordinate gene expression and population responses for survival. This process regulates critical functions like virulence and antibiotic resistance in microbes.

More Related Videos

Using Coculture to Detect Chemically Mediated Interspecies Interactions
08:29

Using Coculture to Detect Chemically Mediated Interspecies Interactions

Published on: October 31, 2013

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
11:31

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Published on: June 30, 2016

Related Experiment Videos

Last Updated: May 25, 2026

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

Using Coculture to Detect Chemically Mediated Interspecies Interactions
08:29

Using Coculture to Detect Chemically Mediated Interspecies Interactions

Published on: October 31, 2013

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
11:31

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Published on: June 30, 2016

Area of Science:

  • Microbiology
  • Molecular Biology
  • Biochemistry

Background:

  • Microorganisms communicate using quorum sensing, a process of cell-density-dependent gene expression.
  • This phenomenon allows microbes to synchronize responses to environmental challenges and optimize survival.
  • Quorum sensing regulates crucial microbial behaviors, including virulence, biofilm formation, and antibiotic resistance.

Purpose of the Study:

  • To review the theoretical aspects of cellular and quorum-sensing mechanisms.
  • To elucidate how quorum sensing affects microbial physiology and pathobiology.
  • To highlight the role of signal transduction pathways in regulating microbial communication.

Main Methods:

  • Literature review of studies on microbial cell-to-cell communication.
  • Analysis of quorum-sensing molecules, their synthesis, secretion, and perception.
  • Examination of signal transduction pathways controlling microbial behavior.

Main Results:

  • Quorum sensing involves coordinated gene expression in response to signal molecule concentrations.
  • It enables microbes to adapt and survive in dynamic environments by linking cellular functions to community needs.
  • Diverse small molecules mediate bacterial communication, impacting virulence, biofilm maturation, and antibiotic resistance.

Conclusions:

  • Quorum sensing is a fundamental social behavior in microbes, crucial for regulating diverse cellular functions.
  • Understanding quorum-sensing mechanisms is vital for comprehending microbial pathobiology.
  • Complex signal transduction pathways tightly control quorum sensing, affecting microbial survival and interaction.