Primary ovarian insufficiency: relation to changes in body composition and adiposity
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Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model
Published on: March 5, 2022
Konstantinos Michalakis1, Simon W Coppack
1East London Obesity Service, Barts & The London School of Medicine, London E1 4AT, United Kingdom.
Abstract:
There are several causes of primary ovarian insufficiency (POI) but all result in a premature cessation of female reproductive potential, mimicking the normal menopause. In normal menopause, there is increased cardiovascular risk associated with changes in body composition (specifically increasing adiposity). We sought to review the literature on POI in relation to changes in adiposity and related cardiometabolic risk factors. We conclude that POI patients are usually less obese than reference groups.
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